Pap classificatie



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Ocular manifestations are common, and range from symptoms of burning or itching to signs of conjunctival hyperemia and lid inflammation. Styes, chalazia, and corneal damage may occur in many patients with rosacea in addition to cutaneous stigmata. The severity of ocular manifestations may not be proportional to those of the skin. Rosacea has been reported to occur in other locations, 5 but the frequency and occurrence of this are ill-defined. Rosacea in peripheral locations may or may not be accompanied by facial manifestations. These can include patulous follicles, skin thickening or fibrosis, and a bulbous appearance. Rhinophyma is the most common form, but other phymas may occur (Table I).

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Nodules may also occur. Although patients with concomitant acne may exhibit comedones, comedones should be considered part of an acne process unrelated to rosacea. Telangiectases are common but not necessary for a rosacea diagnosis. Secondary features The following signs and symptoms often appear with one or more of the primary features of rosacea, but in some patients can occur independently. Burning or stinging sensations with or without scaling or dermatitis may occur, especially on malar skin.

Elevated red plaques without epidermal changes in the surrounding skin may occur. Central facial skin may be rough and scaling so as to resemble dry skin and suggest an eczematous dermatitis, and may often include the coexistence of seborrheic dermatitis. This dryness may be associated with burning or stinging sensations, and may be caused by irritation rather than the disease process. Edema may accompany recepten or follow prolonged facial erythema or flushing. Sometimes soft edema may last for days or be aggravated by inflammatory changes. Solid facial edema (persisting hard, nonpitting edema) can occur with rosacea, usually as a sequel of the papulopustular type, and also independently of redness, papules and pustules, or phymatous changes.

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The following provisional classification system describes the primary features of rosacea and defines 4 subtypes and 1 variant. Evolution from one subtype to another may or may not occur, and research to investigate this process may provide important insight into the pathogenesis of rosacea. Regardless of subtype, however, each individual characteristic may progress from mild to moderate to severe. Early diagnosis and treatment are therefore recommended. Primary features Rosacea typically affects the convexities of the central face.


The presence of one or more of the following signs with a central face distribution is indicative of rosacea. These signs are commonly transient, and each may occur independently. Many patients may present with more than one of these diagnostic features. A history of frequent blushing or flushing is common. Persistent redness of the facial skin is the most common sign of rosacea. Dome-shaped red papules with or without accompanying pustules, often in crops, are typical.

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Rosacea occurs in both men and slecht women and, although it may occur at any age, the onset typically begins at any time after age. 3 Despite its apparent high incidence, the nosology of rosacea is not well established, and the term rosacea has been applied to patients and research subjects with a diverse set of clinical findings that may or may not be an integral part of this disorder. In addition to the diversity of clinical manifestations, the etiology and pathogenesis of rosacea are unknown, and there are no histologic or serologic markers. Therefore, the national Rosacea society assembled a committee to develop a standard classification system that can serve as a diagnostic instrument to investigate the manifestations and relationships of the several subtypes and potential variants of rosacea. Standard criteria for diagnosis and classification of patients are essential to perform research, analyze results and compare data from different sources, and may further serve as a diagnostic reference in clinical practice. The standard terminology will also facilitate clear communication among a broad range of basic, clinical, and other researchers; practicing dermatologists, primary care physicians, ophthalmologists and other specialists; health and insurance administrators; and patients and the general public. The committee based the standard classification system on present scientific knowledge and morphologic characteristics. This avoids assumptions on pathogenesis and progression, and provides a framework that can be readily updated and expanded as new discoveries are made. As knowledge increases, it is hoped that the definition of rosacea may ultimately be based on causality, rather than on morphology alone.

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Reprint requests: The national, rosacea. Society, 196 James., barrington, il 60010. J am Acad Dermatol 2002;46:584-7 16/1/120625 doi:10.1067/mjd.2002.120625, introduction, rosacea is well recognized as a chronic cutaneous disorder primarily of the convexities of the central face (cheeks, chin, nose, and central forehead often characterized by remissions and exacerbations. Based on present knowledge, it is considered a syndrome, or typology, encompassing various combinations of such cutaneous signs as flushing, erythema, telangiectasia, edema, papules, pustules, ocular lesions, and rhinophyma. 1, in most cases, some rather than all of these stigmata appear in any given patient. Rosacea appears to be quite common, and in an epidemiologic study in Sweden its mogelijk prevalence was. 2, it has been most frequently observed in patients with fair skin, but has also been diagnosed in Asians and African Americans.



Note: In 2017, a new standard classification and pathophysiology of rosacea was published in the, journal of the American Academy pillen of Dermatology, accompanied by a commentary on rosacea comorbidities and future research. Developed by a consensus committee and review panel of 28 rosacea experts worldwide, the updated system is based on the substantial advances in the understanding of rosacea gained through scientific investigations over the last 15 years. April 2002 volume 46 number. Special Report, standard classification of rosacea : Report of the national, rosacea. Society Expert Committee on the Classification and Staging. Rosacea, jonathan Wilkin, md chairmana, mark dahl, mdb, michael Detmar, mdc. Lynn Drake, mdc, alvan feinstein, mdd, richard Odom, mde. Frank powell, mdf, sections, from the division of Dermatologic and Dental Drug Products, food and Drug Administration, rockvillea; the department of Dermatology, mayo clinic Scottsdaleb; the department of Dermatology, harvard Medical School, bostonc; the departments of Medicine and Epidemiology and Public health, yale University, new. The opinions set forth in this report are those of the committee members and do not represent the food and Drug Administration in any way.

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Pap classificatie
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Recensies voor het bericht pap classificatie

  1. Ipesef hij schrijft:

    north Holland, Amsterdam, 1989. In: Primary care research: theory and methods. In: weiss bd,. Huisbezoek in de grote stad.

  2. Adusofy hij schrijft:

    Étude de cas du csb centre ville à kalaa kebira, sousse. Medical counseling through computer communication networks. Eur j clin Pharmacol, 1998 Jun;54(4 333-6.



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